The Berryman Marathon and 50 Miler, set for May 16, 2026, invites runners to experience the demanding yet rewarding single-track trails of Missouri's Mark Twain National Forest, nestled near Potosi. Participants can choose between conquering one 26.4-mile loop for the marathon or tackling two loops for the formidable 50-mile ultra-marathon. The course is renowned for its continuously rolling hills and moderately technical terrain, featuring abundant rocks and roots, and delivering a significant 2500 feet of elevation gain and loss per loop. The historic Berryman Trail, designated a National Recreation Trail in 1980, offers a captivating journey through an entirely forested landscape of pine, oak, and bottomland hardwoods, ensuring ample shade and picturesque scenery throughout. Prepare for multiple creek crossings, including the notable Brazil Creek, which is typically shin-deep.

This iconic event, formally established in 2000 by the Saint Louis Ultrarunners Group (SLUGs), has earned a reputation as a "tough trail race" that truly tests a runner's endurance. Aid stations are strategically positioned approximately every 5 to 6 miles, providing water, Hylē sports drink, soda, and an assortment of ultra snacks. As a cupless race, runners are required to carry their own hydration vessels. Typical race day conditions in mid-May see highs around 74F and lows around 54F, with a 22% chance of precipitation, offering a generally favorable but potentially humid setting. The race begins and concludes at the primitive Berryman Campground, providing a rustic and authentic trail running experience, and offers valuable ITRA points for finishers.