Embark on an unforgettable 100-mile journey at the C&O Canal 100, set for April 25, 2026, in scenic Knoxville, MD. This renowned ultramarathon offers an exceptionally flat and fast course, making it a prime destination for both seasoned veterans seeking a personal best and aspiring first-time 100-mile finishers. The race unfolds almost entirely along the historic C&O Canal towpath, a packed dirt surface that gracefully parallels the majestic Potomac River, offering continuous riverside views and glimpses of the Appalachian mountains. While the course boasts minimal elevation gain, runners will experience a memorable 260-foot single-track descent from Camp Manidokan at the start, which they will ascend to reach the finish line after each of the event's three loops – one approximately 40-mile loop followed by two roughly 30-mile loops.

Runners can anticipate well-supported aid stations, spaced every 3 to 6.9 miles, offering a generous array of nutrition including Tailwind, Honey Stinger, and typical ultrarunning staples like chips, pretzels, fruits, and warm soups. Electronic timing at all aid stations allows for live tracking, keeping crews and loved ones updated on progress. The C&O Canal 100 stands out not only for its smooth, non-technical terrain, which is largely shaded, but also for its rich historical backdrop, running through areas steeped in Civil War history near the Antietam National Battlefield. Typical race day conditions in late April bring comfortable highs around 69°F and lows around 46°F, with an approximately 18% chance of precipitation, providing a generally temperate climate for a long-distance effort.

This Western States Endurance Run qualifier is celebrated for its superb organization and the unwavering enthusiasm of its volunteers, who are consistently praised for their support and dedication. Beginning and concluding at Camp Manidokan, the race fosters a welcoming atmosphere with available camping and a rewarding post-race meal. The C&O Canal 100 is more than just a race; it's an immersive experience along a historically significant waterway, perfect for pushing limits and forging unforgettable memories on the trail.