Prepare for a Valentine's weekend like no other at Cupid's Undie Run - Orlando, a lively 1-mile dash set to ignite the streets of downtown Orlando on February 21, 2026. This isn't just a run; it's a "no-pants party" with a purpose, where participants strip down to their undies or creative costumes to raise awareness and critical funds for Neurofibromatosis (NF) research. The event kicks off and concludes at Elixir Kitchen and Bar at 9 W. Washington St., transforming the heart of Orlando into a vibrant celebration of charity and courage.

The Cupid's Undie Run is renowned for its unique, high-energy atmosphere, making it one of the most ridiculous and memorable "mile(ish)" runs you'll ever experience. It begins with a festive pre-party featuring drinking and dancing, followed by the fun run along temporarily closed downtown roads, offering an urban backdrop to your cheeky sprint. The event wraps up with an epic dance party, ensuring the fun continues long after you cross the finish line. Typical race day conditions in Orlando around this time of year are pleasant, with highs averaging 76F and lows around 56F, and only an 8% chance of precipitation, making for ideal running (or dancing) weather.

More than just a good time, this event carries a powerful message of solidarity for those affected by NF, a genetic disorder causing tumors to grow on nerves throughout the body. Since its inception in 2010, Cupid's Undie Run has expanded to over 30 cities and has proudly raised over $21.7 million for the Children's Tumor Foundation, a highly-rated charity dedicated to finding a cure for NF. Join fellow "heroes, party animals, and undie-lovers" in this spirited dash to make a tangible difference in the lives of millions.