Lace up your running shoes for the Miles for Meso 5K, a truly impactful race returning to historic Alton, Illinois, on Saturday, September 19, 2026. This longstanding community event, also featuring a 3K Fun Run/Walk, is renowned for its challenging course and vibrant atmosphere, all while supporting a vital cause. Runners will navigate Alton's unique brick streets and rolling hills, enjoying scenic views of the Mississippi River. The course is known for its difficulty, appealing to those seeking a test of endurance. Typical race day conditions in mid-September offer comfortable highs around 81F and lows near 57F, with only a 9% chance of precipitation, creating a pleasant environment for both competitive runners and casual participants.

Beyond the challenge, the Miles for Meso 5K stands out for its profound mission. Since its inception in 2009, the race has raised over $977,500 for mesothelioma research and awareness through the Asbestos Disease Awareness Organization (ADAO), directly impacting patients and families. Participants receive a commemorative finisher medal and a long-sleeve, moisture-wicking T-shirt, with competitive 5K runners eligible for cash prizes and age group awards. The festivities kick off at One Court Street, outside the Simmons Hanly Conroy national headquarters, and include a lively vendor fair and family-friendly activities, fostering a powerful sense of community and support for those affected by asbestos-related diseases.