Get ready to discover the charm of Cape Girardeau, Missouri, at the 6th Annual Muddy River Half Marathon on Saturday, May 2, 2026. This popular event offers both a 13.1-mile individual half marathon and a half marathon relay, inviting runners of all levels to experience a scenic and engaging course. Typical race day conditions in early May feature pleasant highs around 73°F and lows near 52°F, with a 20% chance of precipitation, creating ideal running weather.

The Muddy River Half Marathon boasts a course that is largely flat, utilizing a mix of roadways and paved trails, though runners should be prepared for some rolling hills and elevation changes, particularly in later sections. As you navigate the route, you'll be treated to iconic Cape Girardeau landmarks such as the Bill Emerson Bridge, the historic Common Pleas Courthouse, and Old St. Vincent's Church. The race culminates with a festive finish at the riverfront, conveniently located near the Century Casino. Aid stations are well-equipped with water, Gu, and Tailwind approximately every two miles to keep you energized.

Beyond the race itself, the Muddy River Half Marathon is deeply rooted in community spirit, having raised over $100,000 for local non-profits since its inception. Participants frequently praise the event's excellent organization, enthusiastic volunteers, and high-quality race swag, including a distinctive medal and performance apparel. Whether you're chasing a personal best or looking for a memorable race experience with a vibrant atmosphere, this event promises an unforgettable journey through Cape Girardeau's historic landscapes, all while supporting a great cause.