Run4Life 5K

Lace up your running shoes for the 19th Annual Run4Life 5K, a cherished Greenville tradition set for Saturday, November 7, 2026. This inspiring event, held at the Caine Halter Family YMCA, offers a 5K race, a 1-Mile run/walk, and a Kids Run, ensuring a meaningful experience for participants of all ages and abilities. More than just a race, Run4Life is a powerful community gathering dedicated to combating cancer, with every dollar raised directly supporting the Prisma Health Cancer Institute and local cancer research and patient programs.

Runners can anticipate typical race day conditions in early November, with highs around a comfortable 66°F and lows around 44°F, accompanied by only an 11% chance of precipitation, creating an ideal environment for personal bests or a pleasant walk. The course, while generally a road race, takes participants through the vibrant community surrounding the Caine Halter Family YMCA, located at 721 Cleveland St. With chip timing used for the 5K, you can be assured of accurate results as you cross the finish line.

The Run4Life 5K has a proud history, consistently drawing hundreds of participants annually and raising significant funds for a vital cause, including over $145,000 in previous years. It's an uplifting celebration of hope and resilience, organized in partnership with The Neighborhood Cancer Connection and the Caine Halter Family YMCA. Parking is available at the YMCA and nearby churches, and convenient packet pickup takes place at the YMCA in the days leading up to the event and on race morning. Join fellow runners and walkers to make a tangible difference in the fight against cancer.