Unleash the SHE 5K / 10K , presented by MAYO CLINIC

Lace up your running shoes for the Unleash the SHE 5K / 10K, presented by MAYO CLINIC, taking place on April 25, 2026, in Rochester, MN. This celebrated event offers both a 10K and a 5K distance, along with a 2-mile walk and a Kids 1K, inviting participants of all ages and abilities to join. The scenic course winds along the beautiful trails and tree-lined neighborhoods surrounding Cascade Lake, culminating in a festive celebration finish right at Little Thistle Brewing Co.. Typical race day conditions in late April offer pleasant highs around 59F and lows of 38F, with a 17% chance of precipitation, creating ideal running weather.

More than just a race, Unleash the SHE is a vibrant celebration of women's Strength, Health, and Empowerment, though it is proudly open to everyone—men, women, kids, and non-binary individuals are all encouraged to participate and show their support. Organized by the experienced Med City Marathon team, it stands as the largest 5K running race in the Rochester community outside of the marathon weekend. Runners consistently describe the event as a positive, uplifting, and fun experience, with courses suitable for both beginners and seasoned athletes.

Participants can look forward to incredible swag, including custom hoodies or quarter-zips, racer camping mugs, neck buffs, and finisher medals. The post-race celebration at Little Thistle Brewing Co. features live music, and complimentary beverages for all finishers. A key highlight of this event is its commitment to a vital cause: proceeds benefit the Minnesota Ovarian Cancer Alliance (MOCA), directly supporting individuals and families affected by ovarian cancer. Join the enthusiastic crowd, don your favorite super-SHE costumes or teal tutus, and experience a race that combines community spirit with a meaningful mission.